• July 7 , 2021

    Rare genetic variants confer largest increase in type 2 diabetes risk seen to date

    Scientists at the University of Cambridge have identified rare genetic variants—carried by one in 3,000 people—that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect.
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  • July 6 , 2021

    Researchers discover way to improve immune response

    Melbourne researchers have identified a way to improve the immune response in the face of severe viral infections.
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  • July 5 , 2021

    Structures discovered in brain cancer patients can help fight tumors

    Researchers at Uppsala University have discovered lymph node-like structures close to the tumour in brain cancer patients, where immune cells can be activated to attack the tumour. They also found that immunotherapy enhanced the formation of these structures in a mouse model. This discovery suggests new opportunities to regulate the anti-tumour response of t
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  • June 30 , 2021

    Gene therapy breakthrough offers hope to children with rare and fatal brain disease

    Scientists and doctors at University College London Great Ormond Street Institute of Child Health (UCL GOS ICH) and Great Ormond Street Hospital (GOSH) have given hope of a gene therapy cure to children with a rare degenerative brain disorder called Dopamine Transporter Deficiency Syndrome (DTDS).
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  • June 29 , 2021

    New components for antisense gene therapy show promise in treating spinal muscular atrophy

    Skoltech researchers and their colleagues from Russia and the UK investigated the safety and efficacy of new chemistry in antisense oligonucleotides used to treat spinal muscular atrophy (SMA), a debilitating genetic disease. Their results may lead to the development of drugs with less toxicity and fewer injections needed thanks to prolonged action. The pape
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  • June 28 , 2021

    First clinical trial involving in vivo CRISPR human gene editing

    A team of researchers from Intellia Therapeutics, Inc. and Regeneron Pharmaceuticals has conducted the first clinical trial involving in vivo CRISPR human gene editing.
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  • June 25 , 2021

    Hard-working enzyme keeps immune cells in line

    Researchers at La Jolla Institute for Immunology (LJI) have shed light on a process in immune cells that may explain why some people develop cardiovascular diseases.
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  • June 22 , 2021

    Scientists discover novel oncogenic driver gene in human lung cancer

    A research team led by Prof. Wang Yuexiang from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences discovered a novel oncogenic driver gene in human lung cancer, the leading cause of cancer-related mortality worldwide.
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  • June 21 , 2021

    SARS-CoV-2 infections may trigger antibody responses against multiple virus proteins

    A study published in PLOS Biology by Anna Heffron, Irene Ong and colleagues at the University of Wisconsin-Madison, U.S., suggests that immune responses may develop against other proteins produced by the SARS-CoV-2 virus.
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  • June 18 , 2021

    Next-generation T-cell therapeutics set sights on cancers, autoimmune disorders and more

    ​T cells—immune cells that patrol our bodies in search of trouble—have become a central focus for UC San Francisco scientists working on living cell therapies, an approach that views cells themselves as a form of medicine.
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  • June 17 , 2021

    Most cancer cells grown in a dish have little in common with cancer cells in people

    In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.
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  • June 16 , 2021

    Small number of cells could be key enablers of cancer metastasis

    Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists. Working with their research collaborators, the scientists found that 'enabler cells' comprise about 20 percent or less of the cells in an
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