Newsroom
  • August 17 , 2020

    Potency-enhancing drugs linked to decreased risks in men with colorectal cancer

    A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer. PDE5 inhibitors include a few approved drugs in which sildenafil (Viagra) is the most well-known. The article is published in Nature Commu
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  • August 16 , 2020

    Evidence reviews support avoiding opioid prescriptions for sprains and strains

    Two new evidence reviews related to acute musculoskeletal injuries like strains and sprains suggest other forms of treatments are as effective as opioids and have less risk of harms to patients.
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  • August 14 , 2020

    Probe detects the destruction of defective mitochondria

    A versatile probe that can detect with pinpoint accuracy the programmed destruction of defective mitochondria—the powerhouses of cells—has been developed by RIKEN researchers. They used it to show that damaged mitochondria in dopamine-producing neurons fail to be destroyed in mice with a condition resembling Parkinson's disease.
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  • August 13 , 2020

    Experimental treatment confers benefits for the alleviation of nonalcoholic hepatic steatosis

    Prof. Liu Hongwei's group and Prof. Liu Shuangjiang's group from the Institute of Microbiology of the Chinese Academy of Sciences has reported the anti-NAFLD effects of a Ganoderma meroterpene derivative that increased the abundance of Bacteroides spp. to activate Bacteroides-folate-liver pathway and further alleviate nonalcoholic fatty liver disease (NAFLD)
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  • August 12 , 2020

    Flipping a metabolic switch to slow tumor growth

    The enzyme serine palmitoyl-transferase can be used as a metabolically responsive "switch" that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings Aug. 12 in the journal Nature.
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  • August 11 , 2020

    New machine learning tool predicts devastating intestinal disease in premature infants

    Necrotizing enterocolitis (NEC) is a life-threatening intestinal disease of prematurity. Characterized by sudden and progressive intestinal inflammation and tissue death, it affects up to 11,000 premature infants in the United States annually, and 15-30% of affected babies die from NEC. Survivors often face long-term intestinal and neurodevelopmental complic
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  • August 10 , 2020

    Researchers characterize important regulators of tissue inflammation, fibrosis and regeneration

    Although macrophages (cells involved in the detection and destruction of bacteria and other harmful organisms as well as dead cells) are classified as immune cells functioning in the activation and resolution of tissue inflammation, it is now clear that they are critically involved in a variety of disease processes, such as chronic inflammatory diseases, tum
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  • July 30 , 2020

    Researchers discover new set of channels connecting malaria parasite and blood cells

    Researchers at the National Institutes of Health and other institutions have discovered another set of pore-like holes, or channels, traversing the membrane-bound sac that encloses the deadliest malaria parasite as it infects red blood cells. The channels enable the transport of lipids—fat-like molecules—between the blood cell and parasite, Plasmodium falcip
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  • July 30 , 2020

    Investigational breast cancer vaccine plus immune therapy work well in tandem

    A vaccine for HER2-positive breast cancers that is being tested in a clinical trial at Duke Cancer Institute is part of an effective, two-drug strategy for enlisting the immune system to fight tumors, according to a Duke-led study in Clinical Cancer Research, a journal of the American Association for Cancer Research.
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  • July 29 , 2020

    Researchers detangle protein interaction implicated in Down syndrome and Alzheimer's

    From the movement of a finger to the creation of a memory, actions of the human body require the harmonious concert of protein interactions. A system of checks and balances ensures proper coordination of biomolecules, but when the scale is tipped, lopsided molecular relationships can lead to disorders and diseases. Discovering how proteins interact with one
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  • July 29 , 2020

    Engineers find thinner tissues in replacement heart valves create problematic flutter

    You're in the middle of the aorta, the body's pipeline for oxygen-rich blood, looking back toward the heart's primary pump, the left ventricle.
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  • July 28 , 2020

    Artificial intelligence finds patterns of mutations and survival in tumour images

    Researchers at EMBL's European Bioinformatics Institute (EMBL-EBI), the Wellcome Sanger Institute, Addenbrooke's Hospital in Cambridge, UK, and collaborators have developed an artificial intelligence (AI) algorithm that uses computer vision to analyze tissue samples from cancer patients. They have shown that the algorithm can distinguish between healthy and
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