Newsroom
-
August 18 , 2020
Acidic niche keeps lymphatic system in check during immune response
- In the fight against cancer, the immune system is the first line of defense. The lymphatic system specifically is essential to protecting the body against foreign invaders. Activation of immune cells in the lymph nodes leads to the production and release of antibodies, and activation of lymphocytes, including T cells, to battle infection. But little is known
Read more -
August 17 , 2020
Potency-enhancing drugs linked to decreased risks in men with colorectal cancer
- A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer. PDE5 inhibitors include a few approved drugs in which sildenafil (Viagra) is the most well-known. The article is published in Nature Commu
Read more -
August 16 , 2020
Evidence reviews support avoiding opioid prescriptions for sprains and strains
- Two new evidence reviews related to acute musculoskeletal injuries like strains and sprains suggest other forms of treatments are as effective as opioids and have less risk of harms to patients.
Read more -
August 14 , 2020
Probe detects the destruction of defective mitochondria
- A versatile probe that can detect with pinpoint accuracy the programmed destruction of defective mitochondria—the powerhouses of cells—has been developed by RIKEN researchers. They used it to show that damaged mitochondria in dopamine-producing neurons fail to be destroyed in mice with a condition resembling Parkinson's disease.
Read more -
August 13 , 2020
Experimental treatment confers benefits for the alleviation of nonalcoholic hepatic steatosis
- Prof. Liu Hongwei's group and Prof. Liu Shuangjiang's group from the Institute of Microbiology of the Chinese Academy of Sciences has reported the anti-NAFLD effects of a Ganoderma meroterpene derivative that increased the abundance of Bacteroides spp. to activate Bacteroides-folate-liver pathway and further alleviate nonalcoholic fatty liver disease (NAFLD)
Read more -
August 12 , 2020
Flipping a metabolic switch to slow tumor growth
- The enzyme serine palmitoyl-transferase can be used as a metabolically responsive "switch" that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings Aug. 12 in the journal Nature.
Read more -
August 11 , 2020
New machine learning tool predicts devastating intestinal disease in premature infants
- Necrotizing enterocolitis (NEC) is a life-threatening intestinal disease of prematurity. Characterized by sudden and progressive intestinal inflammation and tissue death, it affects up to 11,000 premature infants in the United States annually, and 15-30% of affected babies die from NEC. Survivors often face long-term intestinal and neurodevelopmental complic
Read more -
August 10 , 2020
Researchers characterize important regulators of tissue inflammation, fibrosis and regeneration
- Although macrophages (cells involved in the detection and destruction of bacteria and other harmful organisms as well as dead cells) are classified as immune cells functioning in the activation and resolution of tissue inflammation, it is now clear that they are critically involved in a variety of disease processes, such as chronic inflammatory diseases, tum
Read more -
July 30 , 2020
Researchers discover new set of channels connecting malaria parasite and blood cells
- Researchers at the National Institutes of Health and other institutions have discovered another set of pore-like holes, or channels, traversing the membrane-bound sac that encloses the deadliest malaria parasite as it infects red blood cells. The channels enable the transport of lipids—fat-like molecules—between the blood cell and parasite, Plasmodium falcip
Read more -
July 30 , 2020
Investigational breast cancer vaccine plus immune therapy work well in tandem
- A vaccine for HER2-positive breast cancers that is being tested in a clinical trial at Duke Cancer Institute is part of an effective, two-drug strategy for enlisting the immune system to fight tumors, according to a Duke-led study in Clinical Cancer Research, a journal of the American Association for Cancer Research.
Read more -
July 29 , 2020
Researchers detangle protein interaction implicated in Down syndrome and Alzheimer's
- From the movement of a finger to the creation of a memory, actions of the human body require the harmonious concert of protein interactions. A system of checks and balances ensures proper coordination of biomolecules, but when the scale is tipped, lopsided molecular relationships can lead to disorders and diseases. Discovering how proteins interact with one
Read more -
July 29 , 2020
Engineers find thinner tissues in replacement heart valves create problematic flutter
- You're in the middle of the aorta, the body's pipeline for oxygen-rich blood, looking back toward the heart's primary pump, the left ventricle.
Read more